{"product_id":"cst-3530s","title":"CST,  3530S, SDF1\/CXCL12 (D32F9) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying SDF-1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, SDF1\/CXCL12 (D32F9) Rabbit Monoclonal Antibody (CST #3530) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSDF1\/CXCL12 (D32F9) Rabbit Monoclonal Antibody detects recombinant SDF1\/CXCL12 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to carboxy-terminal residues of human SDF1\/CXCL12.\n\u003cb\u003eBackground\u003c\/b\u003e\nThe stromal cell derived factor 1 (SDF1\/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors (1). The SDF1\/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells (2). SDF1\/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells (3,4). Many cancer cells express CXCR4, suggesting that SDF1\/CXCL12 plays a role in cancer metastasis (5,6). Alternative splicing and differential processing during maturation produce a pair of SDF1\/CXCL12 isoforms (SDF1\/CXCL12α and SDF1\/CXCL12β) that have different properties and biological activities (7). Additional isoforms of SDF1\/CXCL12 have been reported (8,9).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXCL12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; Pre-B cell growth-stimulating factor; SCYB12; SDF-1; SDF-1-alpha(3-67); SDF-1-beta(3-72); SDF-1a; SDF-1b; SDF1; SDF1A; SDF1B; Stromal cell-derived factor 1; stromal cell-derived factor 1 delta; stromal cell-derived factor 1 gamma; stromal cell-derived factor 1a; TLSF; TLSF-a; TLSF-b; TPAR1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Recombinant protein\nMW (kDa): 9\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799427207337,"sku":"3530S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-3530s","provider":"Iright","version":"1.0","type":"link"}