{"product_id":"cst-38419t","title":"CST,  38419T, DFCP1 (E9Q1S) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying DFCP1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, DFCP1 (E9Q1S) Rabbit Monoclonal Antibody (CST #38419) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nDFCP1 (E9Q1S) Rabbit Monoclonal Antibody recognizes endogenous levels of total DFCP1 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro336 of human DFCP1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nDouble FYVE-containing protein 1 (DFCP1; gene name ZFYVE1), which was identified from a human bone marrow library, contains two carboxyl terminal FYVE domains that function as binding sites for phosphatidylinositol 3-phosphate (PI3P) (1). PI3P generated predominantly by the class III PI3-kinase VPS34 plays a key role in membrane trafficking as well as autophagy (2,3). DFCP1 is primarily localized to the Golgi and endoplasmic reticulum (ER) (4,5). However, during autophagy DFCP1 re-localizes to subdomains of the ER, the omegasome, which become the sites for autophagosome formation (6,7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nDFCP1; Double FYVE-containing protein 1; KIAA1589; phosphoinositide-binding protein SR3; PPP1R172; protein phosphatase 1, regulatory subunit 172; SR3; TAFF1; Tandem FYVE fingers-1; tandem FYVE fingers-1 protein; ZFYV1; ZFYVE1; Zinc finger FYVE domain-containing protein 1; zinc finger FYVE-type containing 1; zinc finger protein, subfamily 2A (FYVE domain containing), 1; zinc finger protein, subfamily 2A, member 1; zinc finger, FYVE domain containing 1; ZNFN2A1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 82\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799462564009,"sku":"38419T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-38419t","provider":"Iright","version":"1.0","type":"link"}