{"product_id":"cst-38635sf","title":"CST,  38635SF, LAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody (BSA and Azide Free)","description":"Monoclonal Antibody for studying C7orf59. Validated for Western Blotting,Immunohistochemistry (Paraffin),Immunofluorescence (Immunocytochemistry). Highly specific and rigorously validated in-house, LAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody (BSA and Azide Free) (CST #38635) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nThis product is the carrier free version of product #13140. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol. This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT\u0026amp;RUN or CUT\u0026amp;Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us . Optimal dilutions\/concentrations should be determined by the end user. BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.\n\u003cb\u003eFormulation\u003c\/b\u003e\nSupplied in 1X PBS (10 mM Na 2 HPO 4 , 3 mM KCl, 2 mM KH 2 PO 4 , and 140 mM NaCl (pH 7.8)). BSA and Azide Free. For standard formulation of this product see product # 13140\n\u003cb\u003eStorage\u003c\/b\u003e\nStore at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze\/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nLAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total LAMTOR4 (C7orf59) protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human LAMTOR4 (C7orf59) protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nLate endosomal\/lysosomal adaptor and MAPK and MTOR activator 4 (LAMTOR4) is an essential component of the ragulator protein complex that is encoded by the gene (1). The ragulator complex also includes LAMTOR1\/C11orf59, LAMTOR2\/ROBLD3, LAMTOR3\/MAPKSP1, and HBXIP (1,2). This pentameric protein complex localizes to the lysosomal membrane and is essential for the lysosomal localization of Rag GTPases and mTORC1 as well as the subsequent activation of mTORC1 in response to amino acid signaling (1-3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC7orf59; LAMTOR4; Late endosomal\/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal\/lysosomal adaptor, MAPK and MTOR activator 4; LOC389541; LTOR4; Ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; UPF0539 protein C7orf59\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 11\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799464202409,"sku":"38635SF","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-38635sf","provider":"Iright","version":"1.0","type":"link"}