{"product_id":"cst-39275s","title":"CST,  39275S, CD69 (E1U2O) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CD69. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CD69 (E1U2O) Rabbit Monoclonal Antibody (CST #39275) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD69 (E1U2O) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD69 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu120 of human CD69 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD69, also known as Leu-23, is a type II transmembrane glycoprotein that is expressed on the surface of T cells, B cells, and NK cells (1,2). This phosphorylated disulfide-linked 28 to 32-kDa homodimer is constitutively expressed on a subset of thymocytes and platelets. It also acts as an activation antigen of lymphocytes, NK cells, neutrophils, and eosinophils (1-6). Studies have shown that stimulation of the T cell receptor (TCR) increases the expression of CD69 on the cell surface. The ability to detect the level of CD69 expression after TCR activation makes CD69 an ideal indicator of T cell activation (1).Â\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nActivation inducer molecule; activation inducer molecule (AIM\/CD69); AIM; BL-AC\/P26; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; CD69; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; EA1; Early activation antigen CD69; early lymphocyte activation antigen; Early T-cell activation antigen p60; GP32\/28; Leukocyte surface antigen Leu-23; MLR-3\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 25-40\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799469510825,"sku":"39275S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-39275s","provider":"Iright","version":"1.0","type":"link"}