{"product_id":"cst-4017s","title":"CST,  4017S, alpha-Amylase Antibody","description":"Polyclonal Antibody for studying Amylase. Validated for Western Blotting. Highly specific and rigorously validated in-house, alpha-Amylase Antibody (CST #4017) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nalpha-Amylase Antibody detects endogenous levels of total α-amylase protein.\nSpecies Reactivity: Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala498 of human carcinoid α-amylase. Antibodies are purified by protein A and peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nα-amylase catalyzes the cleavage of 1, 4-α-D-glucosidic bonds in oligosaccharides and polysaccharides (1). The enzyme is normally produced and secreted in salivary glands (salivary α-amylase or AMY1) and pancreas (pancreatic α-amylase or AMY2A) (1). Studies reported the release of an ectopically expressed α-amylase in certain tumors (1). Furthermore, a new type of α-amylase (carcinoid α-amylase or AMY2B) was identified in a lung carcinoid tissue (2-4). The ectopic expression of α-amylase in a neuroendocrine tumor was also reported (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n1,4-alpha-D-glucan glucanohydrolase 2B; Alpha-amylase 2B; alpha-amylase carcinoid; AMY2; AMY2B; AMY3; amylase alpha 2B; amylase alpha 2B (pancreatic); amylase, alpha 2B (pancreatic); Carcinoid alpha-amylase; glycogenase; HXA\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R\nSENSITIVITY: Endogenous\nMW (kDa): 58\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46800094363817,"sku":"4017S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-4017s","provider":"Iright","version":"1.0","type":"link"}