{"product_id":"cst-4169s","title":"CST,  4169S, TFIIB (2F6A3H4) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying TFIIB. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, TFIIB (2F6A3H4) Mouse Monoclonal Antibody (CST #4169) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nTFIIB (2F6A3H4) Mouse Monoclonal Antibody detects endogenous levels of total TFIIB protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant human TFIIB protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nTFIIB (also known as GTF2B, TF2B and general transcription factor IIB) is a ubiquitously expressed transcription factor that plays a central role in the assembly of the transcription pre-initiation complex through direct recruitment of RNA polymerase II (1,2). TFIIB functions as a bridge between promoter-bound TFIID and RNA polymerase II. In addition to interacting with promoter-bound TFIID and TFIIA, TFIIB makes extensive contacts with the core promoter via two independent DNA-binding modules. TFIIB may also be a target of transcriptional activator proteins that act to stimulate pre-initiation complex assembly.\n\u003cb\u003eAlternate Names\u003c\/b\u003e\ngeneral transcription factor IIB; General transcription factor TFIIB; GTF2B; RNA polymerase II transcription factor IIB; S300-II; TF2B; TFIIB; Transcription initiation factor IIB\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 32\nSource\/Isotype: Mouse IgG2b","brand":"CST","offers":[{"title":"Default Title","offer_id":46799490384041,"sku":"4169S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-4169s","provider":"Iright","version":"1.0","type":"link"}