{"product_id":"cst-42383s","title":"CST,  42383S, TAPBPR (E5P1F) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying TAPBPL. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, TAPBPR (E5P1F) Rabbit Monoclonal Antibody (CST #42383) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nTAPBPR (E5P1F) Rabbit Monoclonal Antibody recognizes endogenous levels of total TAPBPR protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with human TAPBPR recombinant protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nTAPBPR (Tapasin-related protein, TAPBPL) is a type I transmembrane protein expressed primarily in the endoplasmic reticulum (ER) and Golgi apparatus of T cells, B cells, monocytes, and dendritic cells (1,5). TAPBPR acts as a molecular chaperone for major histocompatibility complex class I (MHC class I) and plays a role in the MHC class I-restricted antigen processing and presentation pathway (2-4). TAPBPL has also been described as a novel T cell co-inhibitory molecule and shares both sequence and structural similarities with existing B7 family members of the Ig superfamily (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ10143; TAP binding protein like; TAP binding protein related; TAP binding protein-like; TAP-binding protein-like; TAP-binding protein-related protein; Tapasin-like; TAPASIN-R; Tapasin-related protein; TAPBP-R; TAPBPL; TAPBPR; TPSNR\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 57\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799496544425,"sku":"42383S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-42383s","provider":"Iright","version":"1.0","type":"link"}