{"product_id":"cst-42515t","title":"CST,  42515T, EpCAM (E8Q1Z) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying EPCAM mouse. Validated for WB,IP,IF,IF. Available in 2 sizes. Highly specific and rigorously validated in-house, EpCAM (E8Q1Z) Rabbit Monoclonal Antibody (CST #42515) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunofluorescence (Frozen): 1:800\nImmunofluorescence (Immunocytochemistry): 1:800\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunofluorescence (Frozen), Immunofluorescence (Immunocytochemistry)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg311 of mouse EpCAM protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nEpithelial cell adhesion and activating molecule (EpCAM\/CD326) is a transmembrane glycoprotein that mediates Ca -independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCD326; EGP; EGP-; EGP-2; Egp31; Egp314; Ep-C; Ep-CAM; EpC; EpCA; Epcam; EpCAM1; Epithelial cell adhesion molecule; epithelial glycoprotein 314; GA733-; GA733-2; gp4; gp40; Ly7; Ly74; lymphocyte antigen 74; mEGP314; panepithelial glycoprotein 314; protein 289A; Tacsd1; Tacst; Tacstd1; Trop-1 protein; TROP1; tumor-associated calcium signal transducer 1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 35-45\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799498117289,"sku":"42515T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-42515t","provider":"Iright","version":"1.0","type":"link"}