{"product_id":"cst-42912s","title":"CST,  42912S, CXCL10 (F8S6H) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CXCL10 mouse. Validated for Western Blotting,Flow Cytometry (Fixed\/Permeabilized). Available in 2 sizes. Highly specific and rigorously validated in-house, CXCL10 (F8S6H) Rabbit Monoclonal Antibody (CST #42912) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nFlow Cytometry (Fixed\/Permeabilized): 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Flow Cytometry (Fixed\/Permeabilized)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCXCL10 (F8S6H) Rabbit Monoclonal Antibody recognizes endogenous levels of total CXCL10 protein.\nSpecies Reactivity: Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to mouse CXCL10 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nC-X-C motif chemokine ligand 10 (CXCL10, IP-10) is a chemokine produced by several cell types and induced in response to pro-inflammatory cytokines, such as IFN-gamma and TNF-alpha (1,2). CXCL10 binds to the chemokine receptor CXCR3 and induces calcium flux and cell migration (3). The CXCR3 protein is normally expressed on activated CD4 T cells and NK cells, which can produce pro-inflammatory cytokines, including IFN-gamma and TNF-alpha (3,4). As a result, these molecules act in an amplification loop to promote immune responses in the contexts of both autoimmunity and a tumor immune response (5,6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n10 kDa interferon gamma-induced protein; C-X-C motif chemokine 10; C7; chemokine (C-X-C motif) ligand 10; CRG-; CRG-2; Crg2; Cxcl10; CXL10; Gamma-IP10; gIP-; gIP-10; Ifi; Ifi10; Inp10; interferon activated gene 10; Interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; IP-; IP-10; IP10; mob-; mob-1; Scyb1; Scyb10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; Small-inducible cytokine B10\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R\nSENSITIVITY: Endogenous\nMW (kDa): 10\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800096297129,"sku":"42912S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-42912s","provider":"Iright","version":"1.0","type":"link"}