{"product_id":"cst-45723s","title":"CST,  45723S, BHLHE40\/DEC1 (E6T3E) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying BHLHB2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, BHLHE40\/DEC1 (E6T3E) Rabbit Monoclonal Antibody (CST #45723) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nBHLHE40\/DEC1 (E6T3E) Rabbit Monoclonal Antibody recognizes endogenous levels of total DEC1 protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human DEC1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nDEC1 (BHLHB2, BHLHE40) is a helix-loop-helix (bHLH) transcription factor that plays a role in the circadian system, or mammalian molecular clock (1-6). Its expression is elevated in response to various stimuli such as light pulses, growth factors, or hypoxia. DEC1 is involved in the homeostasis of regulatory T cells and the cellular differentiation, proliferation, and apoptosis of various cancers (4-6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nbasic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix family member e40; basic helix-loop-helix family, member e40; BHE40; BHLHB2; BHLHE40; Class B basic helix-loop-helix protein 2; Class E basic helix-loop-helix protein 40; Clast5; DEC1; differentially expressed in chondrocytes 1; Differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; Enhancer-of-split and hairy-related protein 2; FLJ99214; HLHB2; SHARP-2; SHARP2; Stimulated by retinoic acid gene 13 protein; STRA13; Stra14\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 46\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799523053737,"sku":"45723S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-45723s","provider":"Iright","version":"1.0","type":"link"}