{"product_id":"cst-46003s","title":"CST,  46003S, ZDHHC24 (F9U2B) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying ZDHHC24. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, ZDHHC24 (F9U2B) Rabbit Monoclonal Antibody (CST #46003) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nZDHHC24 (F9U2B) Rabbit Monoclonal Antibody recognizes endogenous levels of total ZDHHC24 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ZDHHC24 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nPalmitoylation, also known as S-acylation, is a posttranslational modification characterized by the reversible addition of fatty acids onto cysteine residues (1). Palmitoylation is typically carried out by a family of transmembrane enzymes known as zinc finger DHHC domain-containing (ZDHHC) proteins (2). One family member in particular, ZDHHC24, has been shown to palmitoylate mitochondrial antiviral signaling protein (MAVS), consequently activating the TBK1-IRF3-interferon (IFN) pathway and promoting antiviral immune responses (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nDHHC-24; Probable palmitoyltransferase ZDHHC24; ZDH24; ZDHHC24; Zinc finger DHHC domain-containing protein 24; zinc finger DHHC-type containing 24; zinc finger, DHHC domain containing 24; zinc finger, DHHC-type containing 24\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 25\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799529017513,"sku":"46003S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-46003s","provider":"Iright","version":"1.0","type":"link"}