{"product_id":"cst-46586w2","title":"CST,  46586W2, CD68 (E3O7V) Rabbit Monoclonal Antibody (SignalFlex™ mFluor™ UV375 Conjugate)","description":"Monoclonal Antibody for studying CD68 mouse. Highly specific and rigorously validated in-house, CD68 (E3O7V) Rabbit Monoclonal Antibody (SignalFlex\u003csup\u003e™\u003c\/sup\u003e mFluor\u003csup\u003e™\u003c\/sup\u003e UV375 Conjugate) (CST #46586) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nSignalFlex™ conjugates are produced using highly validated Cell Signaling Technology Â® primary antibodies and conjugation methods that have been rigorously tested, ensuring high-quality conjugates and lot-to-lot consistency. These conjugates are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity. However, they are not tested on specific assays. Optimal dilutions\/concentrations should be determined by the end user. When performing flow cytometry, we recommend using an isotype control conjugate at the same concentration as the antibody conjugate.\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg\/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD68 (E3O7V) Rabbit mAb (SignalFlex™ mFluor™ UV375 Conjugate) recognizes endogenous levels of total CD68 protein. Staining of uncertain specificity in mouse endometrial epithelium has been observed by immunohistochemistry.\nSpecies Reactivity: Mouse, Rat, Hamster\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with mouse CD68 recombinant protein and reacts with an epitope surrounding Gly113.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCd68; CD68 antigen; gp11; gp110; Lamp4; Macrosialin; Sca; Scard1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R Hm\nSENSITIVITY: Endogenous\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800409002153,"sku":"46586W2","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-46586w2","provider":"Iright","version":"1.0","type":"link"}