{"product_id":"cst-46788v4","title":"CST,  46788V4, PathScan® RP Phospho-Cofilin (Ser3) Sandwich ELISA Kit","description":"ELISA Kit for studying cofilin 1 (Ser3) phosphate in the research area.\n\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: ELISA+\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nThe PathScan\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eBackground\u003c\/b\u003e\nCofilin and actin-depolymerization factor (ADF) are members of a family of essential conserved small actin-binding proteins that play pivotal roles in cytokinesis, endocytosis, embryonic development, stress response, and tissue regeneration (1). In response to stimuli, cofilin promotes the regeneration of actin filaments by severing preexisting filaments (2). The severing activity of cofilin is inhibited by LIMK or TESK phosphorylation at Ser3 of cofilin (3-5). Phosphorylation at Ser3 also regulates cofilin translocation from the nucleus to the cytoplasm (6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n18 kDa phosphoprotein; CFL; CFL1; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); Cofilin-1; Cofilin, non-muscle isoform; epididymis secretory protein Li 15; HEL-S-15; p18\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M","brand":"CST","offers":[{"title":"Default Title","offer_id":46800605085865,"sku":"46788V4","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-46788v4","provider":"Iright","version":"1.0","type":"link"}