{"product_id":"cst-48913s","title":"CST,  48913S, ARPC5 (F5F6V) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying ARPC5. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, ARPC5 (F5F6V) Rabbit Monoclonal Antibody (CST #48913) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nSimple Western™: 1:10 - 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nARPC5 (F5F6V) Rabbit Monoclonal Antibody recognizes endogenous levels of total ARPC5 protein. This antibody cross-reacts with ARPC5L protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to full-length human ARPC5 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nActin-related protein 2\/3 complex subunit 5 (ARPC5) is a component of the ARP2\/3 actin nucleation complex, which regulates actin dynamics and cellular processes such as cell migration, division, endocytosis, and vesicle trafficking (1). The ARP2\/3 complex has also been shown to promote repair of DNA double-strand breaks through homologous recombination (2). ARPC5 expression is increased and associated with poor prognosis in several human cancers, including hepatocellular carcinoma, prostate cancer, gliomas, and multiple myeloma (3-6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nactin related protein 2\/3 complex subunit 5; actin related protein 2\/3 complex, subunit 5, 16kDa; Actin-related protein 2\/3 complex subunit 5; ARC16; Arp2\/3 complex 16 kDa subunit; Arp2\/3 protein complex subunit p16; ARPC5; dJ127C7.3; MGC88523; p16-ARC\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 16\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799655960745,"sku":"48913S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-48913s","provider":"Iright","version":"1.0","type":"link"}