{"product_id":"cst-49392t","title":"CST,  49392T, DOCK2 (E7X1P) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying DOCK2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, DOCK2 (E7X1P) Rabbit Monoclonal Antibody (CST #49392) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nDOCK2 (E7X1P) Rabbit Monoclonal Antibody recognizes endogenous levels of total DOCK2 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human DOCK2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nDOCK2 (dedicator of cytokinesis 2) is a member of the DOCK-A subfamily of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins (1,3). Expressed in leukocytes, DOCK2 activates isoforms of Rac which regulate chemotaxis as part of the immune response (1,2,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\ndedicator of cyto-kinesis 2; dedicator of cytokinesis 2; Dedicator of cytokinesis protein 2; DOCK2; FLJ46592; IMD40; KIAA0209\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 200\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799700557993,"sku":"49392T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-49392t","provider":"Iright","version":"1.0","type":"link"}