{"product_id":"cst-50068s","title":"CST,  50068S, Vasopressin (D8T3K) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Vasopressin. Validated for Immunofluorescence (Frozen). Available in 2 sizes. Highly specific and rigorously validated in-house, Vasopressin (D8T3K) Rabbit Monoclonal Antibody (CST #50068) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nImmunofluorescence (Frozen): 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Immunofluorescence (Frozen)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nVasopressin (D8T3K) Rabbit Monoclonal Antibody recognizes endogenous levels of total Vasopressin protein. Presumed non-specific labeling of retinal plexiform layers has been observed by immunofluorescence.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro155 of human Vasopressin protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nVasopressin is a neuroendocrine peptide that is released to the circulation by magnocellular neurons whose cell bodies are mainly found in the paraventricular and the supraoptic nuclei of the hypothalamus. It was first isolated from pituitary gland extracts and synthesized in 1951 (1). Vasopressin acts by activating G protein-coupled, V1a, V1b (also known as V3) and V2 receptors and plays a fundamental role in the maintenance of water homeostasis. One of its main functions is body water retention (2), hence its alternative name antidiuretic hormone or ADH. Vasopressin also leads to increased arterial blood pressure by raising peripheral vascular resistance (3). Vasopressin is also involved in other physiological processes such as acute heart failure (4), pain (5), and metabolic syndrome (6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nADH; antidiuretic hormone; Arg-vasopressin; arginine vasopressin; Arginine-vasopressin; ARVP; AVP; AVP-NPII; AVRP; Copeptin; NEU2; neurohypophyseal; Neurophysin 2; Neurophysin-II; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; vasopressin; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin; VP\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800295592105,"sku":"50068S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-50068s","provider":"Iright","version":"1.0","type":"link"}