{"product_id":"cst-50308s","title":"CST,  50308S, TAF6L (F3Q9O) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying TAF6L. Validated for Western Blotting,Immunoprecipitation,Chromatin IP. Available in 2 sizes. Highly specific and rigorously validated in-house, TAF6L (F3Q9O) Rabbit Monoclonal Antibody (CST #50308) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nFor optimal ChIP results, use 5 μL of antibody and 10 μg of chromatin (approximately 4 × 10 6 cells) per IP. This antibody has been validated using SimpleChIP ® Enzymatic Chromatin IP Kits.\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\nChromatin IP: 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Chromatin IP\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nTAF6L (F3Q9O) Rabbit Monoclonal Antibody recognizes endogenous levels of total TAF6L protein. This antibody detects a 250 kDa and a 19 kDa protein of unknown identity in some cell lines.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu598 of human TAF6L protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nTATA-box binding protein associated factor 6 like (TAF6L) and TAF5L are components of the SAGA complex, a histone acetyltransferase-containing complex that controls transcription by activation of target genes through histone acetylation (1). TAF6L and TAF5L are capable of activating c-Myc and Oct-4 and their downstream targets, controlling self-renewal in embryonic stem cells (2). TAF6L has been identified as a marker for glioma and bladder cancer (3,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ11136; MGC4288; p300\/CBP-associated factor (PCAF)-associated factor 65; PAF65-alpha; PAF65A; PCAF-associated factor 65 alpha; PCAF-associated factor 65-alpha; TAF6-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 6L; TAF6-like RNA polymerase II, p300\/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF6L; TATA-box binding protein associated factor 6 like\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 65\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799759605929,"sku":"50308S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-50308s","provider":"Iright","version":"1.0","type":"link"}