{"product_id":"cst-51586t","title":"CST,  51586T, KLF5 (D7S3F) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying KLF5. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, KLF5 (D7S3F) Rabbit Monoclonal Antibody (CST #51586) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nKLF5 (D7S3F) Rabbit Monoclonal Antibody recognizes endogenous levels of total KLF5 protein.\nSpecies Reactivity: Human, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala167 of human KLF5 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nKruppel-like factors (KLFs) are a family of zinc finger DNA-binding proteins that share homology to Kruppel transcription factor in (1). These transcription regulators play diverse roles in cell proliferation, differentiation, inflammation, and pluripotency (2). Various KLFs, including KLF5, are involved in cancer-related processes, such as epithelial-mesenchymal transition (EMT), invasion, and metastasis (3-6). In addition, studies show that KLF5 deficiency specific to renal collecting duct epithelial cells impairs cardiac stress adaptation response coordinated by the heart and kidney (7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n(intestinal Kruppel-like factor; basic transcription element binding protein 2; Basic transcription element-binding protein 2; BTE-binding protein 2; BTEB2; CKLF; Colon krueppel-like factor; colon kruppel-like factor; epididymis secretory sperm binding protein; GC box binding protein 2; GC-box-binding protein 2; IKLF; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; KLF5; Krueppel-like factor 5; Kruppel like factor 5; Kruppel-like factor 5 (intestinal); Transcription factor BTEB2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H Mk\nSENSITIVITY: Endogenous\nMW (kDa): 60\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799785754793,"sku":"51586T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-51586t","provider":"Iright","version":"1.0","type":"link"}