{"product_id":"cst-51968t","title":"CST,  51968T, NKG7 (E9L8J) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying NKG7 mouse. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, NKG7 (E9L8J) Rabbit Monoclonal Antibody (CST #51968) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNKG7 (E9L8J) Rabbit Monoclonal Antibody recognizes endogenous levels of total mouse NKG7 protein.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val51 of mouse NKG7 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNatural killer cell granule protein 7 (NKG7, also known as GMP-17 and GIG-I) is a novel type 1 integral membrane protein expressed at high levels in lymphocytes, including natural killer (NK) cells, Î³Î´Â T cells, a subset of Î±Î² T cells, lymphokine-activated killer (LAK) cells (1), and activated T regulatory cells (2). NKG7 expression can be induced in neutrophils following GM-CSF treatment (3). NKG7 protein is localized to the membranes of cytotoxic granules. Following target cell-induced NK cell degranulation, NKG7 translocates from granules to the plasma membrane (4). Studies have also shown that NKG7 is significantly upregulated in allograft rejection patients (5-8).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n2500004F03Rik; natural killer cell group 7 sequence; Natural killer cell protein 7; Nkg7; Protein NKG7\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 17\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800101736617,"sku":"51968T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-51968t","provider":"Iright","version":"1.0","type":"link"}