{"product_id":"cst-52170s","title":"CST,  52170S, IL-33 (F7H4J) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IL33 mouse. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, IL-33 (F7H4J) Rabbit Monoclonal Antibody (CST #52170) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIL-33 (F7H4J) Rabbit Monoclonal Antibody recognizes endogenous levels of total IL-33 protein.\nSpecies Reactivity: Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln205 of mouse IL-33 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nIL-33 (Interleukin-33, NF-HEV) is a nuclear cytokine that is part of the IL-1 family (1,2). Originally discovered as the ‘nuclear factor from high endothelial venules,' it is widely expressed by endothelial cells as well as epithelial barrier tissues (1,5). IL-33 is involved in regulating type 2-associated innate immune responses (2,4). It is the ligand for ST2 which, along with IL-1RAcP, forms the IL-33R signaling complex (2,3). IL-33 functions as an alarmin upon cellular damage or stress, and is associated with allergic inflammation and asthma (5,6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n9230117N10Rik; Il-; IL-33; Il1f; Il1f11; Il33; interleukin 33; Interleukin-33; Interleukin-33(102-266); Interleukin-33(109-266); NF-H; NF-HEV; nuclear factor from high endothelial venules\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R\nSENSITIVITY: Endogenous\nMW (kDa): 18, 25-30\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800101867689,"sku":"52170S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-52170s","provider":"Iright","version":"1.0","type":"link"}