{"product_id":"cst-52181s","title":"CST,  52181S, CD205\/DEC-205 (F1N2F) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying DEC-205. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, CD205\/DEC-205 (F1N2F) Rabbit Monoclonal Antibody (CST #52181) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nSimple Western™: 1:10 - 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD205\/DEC-205 (F1N2F) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD205\/DEC-205 protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CD205\/DEC-205 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nDEC-205 (LY75, CD205) is an endocytic type I, C-type lectin-like member of the macrophage mannose receptor family (1-7). It is a type I membrane protein, expressed primarily in dendritic cells and thymic epithelial cells (1-3). DEC-205 mediates the endocytosis of antigens (1-7). Once antigens are broken down, they enter the MHC class I or MHC class II presentation pathways and cross-present to T cells, leading to activation of the immune response (4-7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC-type lectin domain family 13 member B; CD205; CLEC13B; DEC-205; gp200-MR6; Ly-75; LY75; Lymphocyte antigen 75\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 205\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799789588649,"sku":"52181S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-52181s","provider":"Iright","version":"1.0","type":"link"}