{"product_id":"cst-53126t","title":"CST,  53126T, CD180\/RP105 (E5D4P) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CD180. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CD180\/RP105 (E5D4P) Rabbit Monoclonal Antibody (CST #53126) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD180\/RP105 (E5D4P) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD180\/RP105 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the extracellular domain of human CD180\/RP105 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD180\/RP105 is a type-I transmembrane glycoprotein that is restricted to expression in mature B cells. Research studies have shown that CD180 engages signaling cascades in mature B cells that drive cell proliferation (1-3). Indeed, CD180 functions with TLR4 as an LPS receptor on B cells and, upon binding LPS, transmits proliferation and survival signals that require the Vav family of guanine nucleotide exchange factors (4-6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCD180; CD180 antigen; CD180 molecule; LY64; Ly78; Lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; MGC126233; MGC126234; Radioprotective 105 kDa protein; RP105\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 98\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799797256361,"sku":"53126T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-53126t","provider":"Iright","version":"1.0","type":"link"}