{"product_id":"cst-5365t","title":"CST,  5365T, PSA\/KLK3 (D6B1) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying PSA (Prostate Specific Antigen). Validated for WB,IP,IF,F. Available in 2 sizes. Highly specific and rigorously validated in-house, PSA\/KLK3 (D6B1) Rabbit Monoclonal Antibody (CST #5365) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunofluorescence (Immunocytochemistry): 1:200\nFlow Cytometry (Fixed\/Permeabilized): 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 35198 .\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunofluorescence (Immunocytochemistry), Flow Cytometry (Fixed\/Permeabilized)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nPSA\/KLK3 (D6B1) Rabbit Monoclonal Antibody recognizes endogenous levels of total PSA\/KLK3 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Phe165 of human PSA\/KLK3 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nKallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases (1). It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 amino-terminal amino acids (2), it is activated to liquefy semen in the seminal coagulum. Although PSA\/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer (2,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAPS; Gamma-seminoprotein; hK3; kallikrein related peptidase 3; Kallikrein-3; kallikrein-related peptidase 3; KLK2A1; KLK3; P-30 antigen; prostate specific antigen; Prostate-specific antigen; PSA; Semenogelase; Seminin\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 29\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799802073257,"sku":"5365T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-5365t","provider":"Iright","version":"1.0","type":"link"}