{"product_id":"cst-5557s","title":"CST,  5557S, Succinyl-CoA Synthetase Antibody","description":"Polyclonal Antibody for studying SUCLG1. Validated for Western Blotting,Immunoprecipitation. Highly specific and rigorously validated in-house, Succinyl-CoA Synthetase Antibody (CST #5557) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSuccinyl-CoA Synthetase Antibody detects endogenous levels of total succinyl-CoA synthetase (Î± subunit) protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human succinyl-CoA synthetase (Î± subunit) protein. Antibodies are purified by protein A and peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nSuccinyl-CoA synthetase Î± subunit (SUCLG1) catalyzes the conversion of succinate to succinyl-CoA and plays a key role in the citric acid cycle (1,2). Deficiency of this enzyme leads to a variety of diseases including fatal infantile lactic acidosis (3) and mitochondrial hepatoencephalomyopathy (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ21114; FLJ43513; GALPHA; MTDPS9; SCS-alpha; SUCA; Succinate--CoA ligase [ADP\/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase alpha subunit; succinate-CoA ligase GDP\/ADP-forming subunit alpha; succinate-CoA ligase, alpha subunit; succinyl-CoA ligase [ADP\/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SUCLA1; SUCLG1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 36\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46799818719401,"sku":"5557S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-5557s","provider":"Iright","version":"1.0","type":"link"}