{"product_id":"cst-57710l","title":"CST,  57710L, Whitlow\/218 Linker (E3U7Q) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying . Validated for Simple Western™,Flow Cytometry (Live). Available in 3 sizes. Highly specific and rigorously validated in-house, Whitlow\/218 Linker (E3U7Q) Rabbit Monoclonal Antibody (CST #57710) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nSimple Western™: 1:10\nFlow Cytometry (Live): 1:100 - 1:400\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 66159 .\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Flow Cytometry (Live)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nWhitlow\/218 Linker (E3U7Q) Rabbit Monoclonal Antibody recognizes exogenously expressed levels of scFv-based CARs containing a Whitlow\/218 linker. This antibody is not approved for traditional Western blot analysis.\nSpecies Reactivity: All Species Expected\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues of the Whitlow\/218 linker peptide.\n\u003cb\u003eBackground\u003c\/b\u003e\nThe Whitlow\/218 peptide is a commonly used linker that connects the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The Whitlow\/218 linker affords the scFv with enhanced resistance to proteolysis and aggregation (1).\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: All\nSENSITIVITY: Transfected Only\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800291528873,"sku":"57710L","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-57710l","provider":"Iright","version":"1.0","type":"link"}