{"product_id":"cst-57755s","title":"CST,  57755S, Mfsd2a Antibody","description":"Polyclonal Antibody for studying MFSD2A mouse. Validated for Western Blotting. Highly specific and rigorously validated in-house, Mfsd2a Antibody (CST #57755) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMfsd2a Antibody recognizes endogenous levels of total Mfsd2a protein.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of mouse Mfsd2a protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nMfsd2a is a sodium-dependent lysophosphatidylcholine symporter (1). It regulates lipid metabolism, growth and development, and motor function (2). It transports lysophosphatidylcholines consisting of omega-3 fatty acid docosahexaenoic acid (DHA) or other long-chain fatty acids. Mfsd2a was shown to be critical for the brain to take up DHA from plasma (3). Furthermore, Mfsd2a is required for the blood-brain barrier (BBB) formation and function (4). Lipids transported into endothelial cells in the central nervous system by Mfsd2a form a lipid environment essential to maintain BBB integrity (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n1700018O18Rik; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; Major facilitator superfamily domain-containing protein 2A; MFS2A; Mfsd; Mfsd2; Mfsd2a; NLS1; OTTMUSP00000009315; Sodium-dependent LPC symporter 1; Sodium-dependent lysophosphatidylcholine symporter 1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 50-60\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46800104751273,"sku":"57755S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-57755s","provider":"Iright","version":"1.0","type":"link"}