{"product_id":"cst-62434s","title":"CST,  62434S, Napsin A (D5P6G) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Napsin A. Validated for Western Blotting,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, Napsin A (D5P6G) Rabbit Monoclonal Antibody (CST #62434) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunohistochemistry (Paraffin): 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNapsin A (D5P6G) Rabbit Monoclonal Antibody recognizes endogenous levels of total napsin A protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human napsin A protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNapsin A is an aspartic proteinase that is expressed in normal lung and kidney (1). In the lung, napsin A is expressed by type II pneumocytes and alveolar macrophages, where it plays a role in processing surfactant protein B (2). Napsin A is expressed in lung adenocarcinomas, where it can be used to identify primary and metastatic lesions with greater sensitivity compared to TTF-1 (3,4). Napsin A expression has also been described in other types of cancer, such as kidney and thyroid cancer (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAsp 4; ASP4; Aspartyl protease 4; KAP; Kdap; kidney-derived aspartic protease-like protein; NAP1; NAPA; NAPSA; napsin A aspartic peptidase; Napsin-1; Napsin-A; pronapsin A; SNAPA; TA01\/TA02\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 31\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46801029103785,"sku":"62434S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-62434s","provider":"Iright","version":"1.0","type":"link"}