{"product_id":"cst-63975v3","title":"CST,  63975V3, PathScan® RP CasMINI Sandwich ELISA Kit","description":"ELISA Kit for studying cas12f bacteria in the research area.\n\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: ELISA+\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nThe PathScan\nSpecies Reactivity: All Species Expected\n\u003cb\u003eBackground\u003c\/b\u003e\nCRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins) are RNA-guided nuclease effectors that are utilized for precise genome editing in mammalian systems (1). Cpf1\/Cas12a (CRISPR from and ) proteins are members of the Class 2 CRISPR system (2). Class 2 CRISPR systems, such as the well characterized Cas9, rely on single-component effector proteins to mediate DNA interference (3). Cpf1\/Cas12a and Class 2 CRISPR endonucleases permit efficient and specific genome editing that may be used as gene therapies for genetic diseases. However, virus-based vehicles used for delivery, like adeno-associated virus (AAV)-based vectors, have a limited packaging capacity. CasMINI was engineered from the naturally occurring type V-F Cas12f (Cas14) system. CasMINI is 529 amino acids, which is significantly smaller than Cpf1\/Cas12a and Cas9 proteins (62% and 57% smaller, respectively), making CasMINI more suitable for virus-based packaging for delivery (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\ncas14a1; CRISPR-associated endodeoxyribonuclease Cas12f1; Un1Cas12f1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: All","brand":"CST","offers":[{"title":"Default Title","offer_id":46800619012265,"sku":"63975V3","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-63975v3","provider":"Iright","version":"1.0","type":"link"}