{"product_id":"cst-64184t","title":"CST,  64184T, NCAM2 (E8J3B) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying NCAM2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, NCAM2 (E8J3B) Rabbit Monoclonal Antibody (CST #64184) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNCAM2 (E8J3B) Rabbit Monoclonal Antibody recognizes endogenous levels of total NCAM2 protein. This antibody does not cross-react with NCAM1.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly261 of human NCAM2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNCAM (neural cell adhesion molecule) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Two NCAM paralogs ( and ) are encoded in the mammalian genome, which encode NCAM\/NCAM1 and NCAM2 proteins, respectively (1,2). As an adhesion molecule with brain-enriched expression, NCAM2 functions to drive axonal targeting, neurite branching, and synaptic development (2-4). is also genetically linked to Down syndrome and may play a role in neurodegenerative diseases such as Alzheimer's disease (2,5).Â\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nMGC51008; N-CAM-2; NCAM-2; NCAM2; NCAM21; Neural cell adhesion molecule 2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 93, 140\nSource\/Isotype: IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799834054825,"sku":"64184T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-64184t","provider":"Iright","version":"1.0","type":"link"}