{"product_id":"cst-67895s","title":"CST,  67895S, SARS-CoV-2 Nsp7 Antibody","description":"Polyclonal Antibody for studying nsp7-pp1a-pp1ab SARS-CoV-2\/nsp7-pp1a-pp1ab SARS-CoV. Validated for Western Blotting. Highly specific and rigorously validated in-house, SARS-CoV-2 Nsp7 Antibody (CST #67895) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSARS-CoV-2 Nsp7 Antibody recognizes transfected levels of total SARS-CoV-2 Nsp7 protein.\nSpecies Reactivity: Virus\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala80 of SARS-CoV-2 Nsp7 protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nThe cause of the COVID-19 pandemic is a novel and highly pathogenic coronavirus, termed SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). SARS-CoV-2 is a member of the Coronaviridae family of viruses (1). The genome of SARS-CoV-2 is relatively large and encodes up to 29 open reading frames (ORFs). These include ORF1a and ORF1b (further processed into 16 non-structural proteins), 9 accessory proteins, and 4 canonical structural proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N) (2). Nsp7 (non-structural protein 7) is derived from ORF1a and ORF1b (2). It functions along with Nsp8, to bind to and cooperate with Nsp12 (RNA-dependent RNA polymerase) to greatly enhance the holoenzyme polymerase activity (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nnon-structural protein 7; Non-structural protein 7; non-structural protein 7 (3860-3942); nsp7; nsp7-pp1a-pp1ab; nsp7-pp1a\/pp1ab; SARS-CoV nsp7; SARS-CoV-2 nsp7\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: Vir\nSENSITIVITY: Transfected Only\nMW (kDa): 10\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46800244375721,"sku":"67895S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-67895s","provider":"Iright","version":"1.0","type":"link"}