{"product_id":"cst-69858s","title":"CST,  69858S, CD200 (E2K4C) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CD200. Validated for Western Blotting,Immunoprecipitation,Flow Cytometry (Live). Available in 2 sizes. Highly specific and rigorously validated in-house, CD200 (E2K4C) Rabbit Monoclonal Antibody (CST #69858) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\nFlow Cytometry (Live): 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Flow Cytometry (Live)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD200 (E2K4C) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD200 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with human CD200 recombinant protein and reacts with an epitope surrounding Pro189.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD200 (OX2) and CD200R (OX2R) are membrane glycoprotein members of the Ig superfamily (1-3). CD200 is expressed by a range of cells, including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells, while its receptor, CD200R, is found on myeloid and T cells (1-5). Interaction between CD200 and CD200R downregulates macrophage function and plays a role in immunosuppression and regulation of anti-tumor immune responses (3-7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nantigen identified by monoclonal antibody MRC OX-2; CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX-2 antigen; OX-2; OX-2 membrane glycoprotein; OX2G\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 45-50\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799864496297,"sku":"69858S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-69858s","provider":"Iright","version":"1.0","type":"link"}