{"product_id":"cst-70695t","title":"CST,  70695T, NKG7 (F4V5I) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying NKG7. Validated for Western Blotting,Immunoprecipitation,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, NKG7 (F4V5I) Rabbit Monoclonal Antibody (CST #70695) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunohistochemistry (Paraffin): 1:100 - 1:400\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 43571 .\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNKG7 (F4V5I) Rabbit Monoclonal Antibody recognizes endogenous levels of total NKG7 protein. Non-specific staining was observed in pancreatic islets by immunohistochemistry.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly161 of human NKG7 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNatural killer cell granule protein 7 (NKG7, also known as GMP-17 and GIG-I) is a novel type 1 integral membrane protein expressed at high levels in lymphocytes, including natural killer (NK) cells, γδ T cells, a subset of αβ T cells, lymphokine-activated killer (LAK) cells (1), and activated T regulatory cells (2). NKG7 expression can be induced in neutrophils following GM-CSF treatment (3). NKG7 protein is localized to the membranes of cytotoxic granules. Following target cell-induced NK cell degranulation, NKG7 translocates from granules to the plasma membrane (4). Studies have also shown that NKG7 is significantly upregulated in allograft rejection patients (5-8).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nG-CSF-induced gene 1 protein; GIG-1 protein; GIG1; GMP-17; granule membrane protein 17; Granule membrane protein of 17 kDa; natural killer cell granule protein 7; natural killer cell group 7 sequence; Natural killer cell protein 7; NKG7; p15-TIA-1; Protein NKG7; Q16617\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 7-25\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799869575337,"sku":"70695T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-70695t","provider":"Iright","version":"1.0","type":"link"}