{"product_id":"cst-71567t","title":"CST,  71567T, RALY (E4T7E) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying RALY. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, RALY (E4T7E) Rabbit Monoclonal Antibody (CST #71567) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nRALY (E4T7E) Rabbit Monoclonal Antibody recognizes endogenous levels of total RALY protein.\nSpecies Reactivity: Human, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val162 of human RALY protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nRALY is a member of the large family of heterogeneous nuclear ribonucleoproteins (hnRNPs). RALY was initially discovered in lethal yellow mice, a condition where heterozygotes display an all yellow coat, obesity, diabetes, and tumors. In this condition, mRNA to the 5' untranslated region of RALY fuses to the agouti transcript (1,2). RALY binds to U-rich elements in coding and non-coding mRNAs undergoing translation (3). RALY has been implicated in certain cancer types, as it can control transcriptional regulation and splicing of E2F1 and PRMT1 mRNAs (4,5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAutoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP associated with lethal yellow protein homolog; hnRNP core protein C-like 2; HNRPCL2; MGC117312; P542; RALY; RALY heterogeneous nuclear ribonucleoprotein; RNA binding protein (autoantigenic, hnRNP-associated with lethal yellow); RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)); RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog); RNA-binding protein (autoantigenic, hnRNP-associated with lethal yellow); RNA-binding protein (autoantigenic); RNA-binding protein Raly\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H Mk\nSENSITIVITY: Endogenous\nMW (kDa): 38\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799874064553,"sku":"71567T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-71567t","provider":"Iright","version":"1.0","type":"link"}