{"product_id":"cst-71578t","title":"CST,  71578T, IFI6 (E8G9G) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IFI6. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, IFI6 (E8G9G) Rabbit Monoclonal Antibody (CST #71578) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIFI6 (E8G9G) Rabbit Monoclonal Antibody recognizes endogenous levels of total IFI6 protein. This antibody does not cross-react with other ISG12 family proteins.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IFI6 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nInterferon alpha-inducible protein 6 (IFI6) belongs to the ISG12 family of proteins and is a small, multipass transmembrane protein localized to mitochondrial membranes (1,2). IFI6 is one of the first interferon-stimulated genes to be identified and research studies have shown that IFI6 regulates apoptotic signaling pathways triggered in response to type-I interferons (3,4). In addition, IFI6 participates in type-I interferon-mediated antiviral signaling by mitigating viral replication (5,6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n6-16; FAM14C; G1P3; Ifi-6-16; IFI6; IFI616; interferon alpha inducible protein 6; Interferon alpha-inducible protein 6; Interferon-induced protein 6-16; interferon, alpha-inducible protein 6; interferon, alpha-inducible protein clone IFI-6-16\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 12\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799874261161,"sku":"71578T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-71578t","provider":"Iright","version":"1.0","type":"link"}