{"product_id":"cst-71825t","title":"CST,  71825T, BTNL9 (F2F8S) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying BTNL9. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, BTNL9 (F2F8S) Rabbit Monoclonal Antibody (CST #71825) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nBTNL9 (F2F8S) Rabbit Monoclonal Antibody recognizes transfected levels of BTNL9 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu522 of human BTNL9 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nButyrophilin-like (BTNL) proteins are part of the immunoglobulin superfamily and are structurally related to B7 proteins that comprise co-stimulatory and co-inhibitory molecules that regulate T cells. Five BTNL family members have been identified in humans, and eight in mice (1). BTNL proteins play an important role in regulating γδT cells, and BTNL-fc fusion proteins and soluble BTNL molecules have been shown to inhibit T cell activation (2,3). The BTNL family member, BTNL9, has been identified as a prognostic marker and possible therapeutic target in multiple malignancies, including uveal melanoma, breast cancer, lung adenocarcinoma (LUAD), and thyroid cancer (4-7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nBTN3; BTN8; BTNL9; butyrophilin 3; butyrophilin like 9; butyrophilin-like 9; Butyrophilin-like protein 9; OTTHUMP00000082750; Q6UXG8; VDLS1900\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Transfected Only\nMW (kDa): 70\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799875440809,"sku":"71825T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-71825t","provider":"Iright","version":"1.0","type":"link"}