{"product_id":"cst-72054s","title":"CST,  72054S, KIFC1 Antibody","description":"Polyclonal Antibody for studying KIFC1. Validated for Western Blotting. Highly specific and rigorously validated in-house, KIFC1 Antibody (CST #72054) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nKIFC1 Antibody recognizes endogenous levels of total KIFC1 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala668 of human KIFC1 protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nKinesin superfamily proteins (KIFs) are molecular motors that drive directional, microtubule-dependent intracellular transport of membrane-bound organelles and other macromolecules (e.g., proteins, nucleic acids). The intracellular transport functions of KIFs are fundamentally important for a variety of cellular functions, including mitotic and meiotic division, motility\/migration, hormone and neurotransmitter release, and differentiation (1-4). Disruptions to KIF-mediated intracellular transport have been linked with a variety of pathologies, ranging from tumorigenesis to defects in higher order brain function such as learning and memory (4-6). Kinesin family member C1 (KIFC1\/HSET) is a minus-end-directed KIF involved in the processing and movement of early endocytic vesicles (7,8), as well as microtubule cross-linking and spindle assembly (9,10).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nHSET; KIFC1; kinesin family member C1; kinesin-like 2; Kinesin-like protein 2; Kinesin-like protein KIFC1; Kinesin-related protein HSET; KNSL2; MGC1202; MGC149736; MGC149737\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 75\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46799876554921,"sku":"72054S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-72054s","provider":"Iright","version":"1.0","type":"link"}