{"product_id":"cst-73269s","title":"CST,  73269S, HLA-E (MEM-E\/02) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying HLA-E. Validated for Western Blotting,Immunohistochemistry (Paraffin),Flow Cytometry (Fixed\/Permeabilized). Highly specific and rigorously validated in-house, HLA-E (MEM-E\/02) Mouse Monoclonal Antibody (CST #73269) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunohistochemistry (Paraffin): 1:125 - 1:500\nFlow Cytometry (Fixed\/Permeabilized): 1:1000 - 1:4000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in PBS (pH 7.4) containing 15 mM sodium azide. Store at 4°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunohistochemistry (Paraffin), Flow Cytometry (Fixed\/Permeabilized)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nHLA-E (MEM-E\/02) Mouse Monoclonal Antibody recognizes endogenous levels of HLA-E protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a recombinant human HLA-E denatured heavy chain.\n\u003cb\u003eBackground\u003c\/b\u003e\nHLA-E (HLA class I histocompatibility antigen, alpha chain E) is a non-classical MHC molecule that is expressed by B and T lymphocytes, natural killer (NK) cells, and macrophages, and is overexpressed in some tumors (1-3). Classical HLA class I molecules (HLA-A, -B, and -C) are highly polymorphic, affecting the peptide binding region (PBR). HLA-E has limited polymorphism that is restricted to two functional versions (3,5). HLA-E is a ligand of CD94\/NKG2A, -B, and -C receptors, which are expressed on NK cells and T cells and play a role in the innate and adaptive immune system (3-5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nDKFZp686P19218; EA1.2; EA2.1; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, E alpha chain; HLA-6.2; HLA-E; HLAE; lymphocyte antigen; major histocompatibility complex, class I, E; MHC; MHC class I antigen E; MHC class Ib antigen; MHC HLA-E alpha-1; MHC HLA-E alpha-2.1; QA1; sHLA-E; Soluble HLA class I histocompatibility antigen, alpha chain E\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 43\nSource\/Isotype: Mouse IgG1","brand":"CST","offers":[{"title":"Default Title","offer_id":46799882551465,"sku":"73269S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-73269s","provider":"Iright","version":"1.0","type":"link"}