{"product_id":"cst-73741t","title":"CST,  73741T, Fc-gammaRIV (E8I7C) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying FCGR4 mouse. Validated for Western Blotting,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, Fc-gammaRIV (E8I7C) Rabbit Monoclonal Antibody (CST #73741) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunohistochemistry (Paraffin): 1:100 - 1:400\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nFc-gammaRIV (E8I7C) Rabbit Monoclonal Antibody recognizes endogenous levels of total mouse FcγRIV protein. This antibody does not cross-react with mouse FcγRIA, FcγRIIA, or FcγRIIB. Non-specific staining was observed in adipose tissue by immunohistochemistry.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with mouse FcγRIV recombinant protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nFcγRIV is an activating Fcγ receptor present in mice but not humans (2). Binding of Fc receptors to IgG, immune complexes, and opsonized particles results in immune cell activation and effector responses (2). FcγRIV is expressed by myeloid cells and binds to IgG2a and IgG2b, but not to IgG1 or IgG3 (1). FcγRIV signals through ITAM-containing FcRγ (2).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n4833442P21Rik; CD16-2; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc gammaRIV; Fc receptor-like 3; Fc receptor, IgG, low affinity IV; Fcgam; FcgammaRIV; Fcgr; Fcgr3a; Fcgr4; FcgRIV; Fcrl3; Low affinity immunoglobulin gamma Fc region receptor III-A; Low affinity immunoglobulin gamma Fc region receptor IV; OTTMUSP00000024985\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 30-40\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800119824553,"sku":"73741T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-73741t","provider":"Iright","version":"1.0","type":"link"}