{"product_id":"cst-75375t","title":"CST,  75375T, MIGA2\/FAM73B (E3D7E) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MIGA2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, MIGA2\/FAM73B (E3D7E) Rabbit Monoclonal Antibody (CST #75375) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMIGA2\/FAM73B (E3D7E) Rabbit Monoclonal Antibody recognizes endogenous levels of total MIGA2\/FAM73B protein. This antibody does not cross-react with MIGA1\/FAM73A protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly80 of human MIGA2\/FAM73B protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMitoguardin 2 (MIGA2), also known as FAM73B, is a mitochondrial outer membrane protein (1-2). MIGA2 and the mitochondrial outer membrane protein MIGA1 (FAM73A) regulate mitochondrial fusion downstream of the mitofusin proteins (1). In addition, MIGA2 interacts with lipid droplets in adipocytes, linking mitochondria to lipid droplets (2). MIGA2 also interacts with the endoplasmic reticulum (ER) membrane protein VAPA or VAPB, enabling endoplasmic reticulum-mitochondria contacts (2,3). Moreover, MIGA2 is essential for the biosynthesis of triacylglycerols and adipocyte differentiation (2).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC9orf54; FA73B; FAM73B; family with sequence similarity 73, member B; FLJ00199; FLJ14596; MIGA2; Mitoguardin 2; Protein FAM73B\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 70, 78\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799891660969,"sku":"75375T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-75375t","provider":"Iright","version":"1.0","type":"link"}