{"product_id":"cst-78043s","title":"CST,  78043S, IFIT2 (F8P1H) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IFIT2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, IFIT2 (F8P1H) Rabbit Monoclonal Antibody (CST #78043) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIFIT2 (F8P1H) Rabbit Monoclonal Antibody recognizes endogenous levels of total IFIT2 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IFIT2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nIFIT2 (Interferon-induced protein with tetratricopeptide repeats 2, ISG54) belongs to the IFIT family of proteins, which consists of four members in humans (IFIT1, IFIT2, IFIT3, and IFIT5) and three members in mice (IFIT1, IFIT2, and IFIT3) (1). IFIT2 expression is transiently induced by exposure to interferons, double-stranded RNA, or viruses (2). IFIT2 has been shown to inhibit translation by binding to the eukaryotic initiation factor 3 (eIF3) (2). In addition, IFIT2 forms a multiprotein complex with the related proteins IFIT1 and IFIT3, which stimulates cell death via a mitochondrial pathway and prevents viral replication (1,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCIG-42; cig42; G10P2; GARG-39; IFI-54; IFI-54K; IFI54; IFIT-2; IFIT2; interferon induced protein with tetratricopeptide repeats 2; Interferon-induced 54 kDa protein; interferon-induced protein 54; Interferon-induced protein with tetratricopeptide repeats 2; Interferon, alpha-inducible protein (MW 54kD); ISG-54 K; ISG-54K; ISG54; P54\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 55\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799904276649,"sku":"78043S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-78043s","provider":"Iright","version":"1.0","type":"link"}