{"product_id":"cst-79406sf","title":"CST,  79406SF, TNFRSF13C\/BAFF-R (E3C1Q) Rabbit Monoclonal Antibody (BSA and Azide Free)","description":"Monoclonal Antibody for studying BAFF-R. Validated for Western Blotting,Immunohistochemistry (Paraffin). Highly specific and rigorously validated in-house, TNFRSF13C\/BAFF-R (E3C1Q) Rabbit Monoclonal Antibody (BSA and Azide Free) (CST #79406) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nThis product is the carrier-free version of product #62518. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol. This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT\u0026amp;RUN, or CUT\u0026amp;Tag assays. If you require a carrier-free formulation for chromatin profiling, please contact us . Optimal dilutions\/concentrations should be determined by the end user. BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.\n\u003cb\u003eFormulation\u003c\/b\u003e\nSupplied in 1X PBS (10 mM Na 2 HPO 4 , 3 mM KCl, 2 mM KH 2 PO 4 , and 140 mM NaCl (pH 7.8)). BSA and Azide Free. For standard formulation of this product see product # 62518.\n\u003cb\u003eStorage\u003c\/b\u003e\nStore at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze\/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nTNFRSF13C\/BAFF-R (E3C1Q) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total TNFRSF13C\/BAFF-R protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TNFRSF13C\/BAFF-R protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nB cell-activating factor (BAFF)-receptor (BAFF-R) is a type III transmembrane protein that is expressed almost exclusively on the surface of normal, mature B cells as well as malignant B cells from various forms of B cell lymphoproliferative disorders (1). Unlike BCMA and TACI, BAFF-R only binds BAFF and this interaction plays a fundamental role in driving B cell survival and proliferation by engaging canonical and non-canonical NF-κB signaling modules (2-4). Because its expression is largely restricted to the B cell lineage, BAFF-R is being investigated as an additional immunotherapeutic target for B cell malignancies (5,6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nB cell-activating factor receptor; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BAFFR; BLyS receptor 3; BR3; BROMIX; CD268; CVID4; MGC138235; prolixin; TNF receptor superfamily member 13C; TNFRSF13C; TR13C; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 38, 50\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799909421225,"sku":"79406SF","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-79406sf","provider":"Iright","version":"1.0","type":"link"}