{"product_id":"cst-80158t","title":"CST,  80158T, CCPG1 (E3C5G) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CCPG1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CCPG1 (E3C5G) Rabbit Monoclonal Antibody (CST #80158) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCCPG1 (E3C5G) Rabbit Monoclonal Antibody recognizes endogenous levels of total CCPG1 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human CCPG1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCCPG1 (cell cycle progression protein 1) was originally identified as a scaffold protein for Rho- specific guanine nucleotide exchange specificity (1). More recently it has been shown to play an important role in ER homeostasis by functioning as a cargo receptor for ER selective autophagy, termed ER-phagy (2). CCPG1 is localized to the ER and is induced by stress (2, 3). It associates with components of autophagy including LC3 family members and the FIP200, a component of the ULK1 complex, facilitating the trafficking of the ER to the autophagosome (2).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCCP8; CCPG1; cell cycle progression 1; cell cycle progression 8 protein; Cell cycle progression protein 1; Cell cycle progression restoration protein 8; CPR8; KIAA1254\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 105-120\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799913779369,"sku":"80158T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-80158t","provider":"Iright","version":"1.0","type":"link"}