{"product_id":"cst-80302t","title":"CST,  80302T, Mfsd2a (E8U2O) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MFSD2A mouse. Validated for Western Blotting,Immunoprecipitation,Immunofluorescence (Frozen). Available in 2 sizes. Highly specific and rigorously validated in-house, Mfsd2a (E8U2O) Rabbit Monoclonal Antibody (CST #80302) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunofluorescence (Frozen): 1:600 - 1:1200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunofluorescence (Frozen)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMfsd2a (E8U2O) Rabbit Monoclonal Antibody recognizes endogenous levels of total Mfsd2a protein.\nSpecies Reactivity: Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of mouse Mfsd2a protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMfsd2a is a sodium-dependent lysophosphatidylcholine symporter (1). It regulates lipid metabolism, growth and development, and motor function (2). It transports lysophosphatidylcholines consisting of omega-3 fatty acid docosahexaenoic acid (DHA) or other long-chain fatty acids. Mfsd2a was shown to be critical for the brain to take up DHA from plasma (3). Furthermore, Mfsd2a is required for the blood-brain barrier (BBB) formation and function (4). Lipids transported into endothelial cells in the central nervous system by Mfsd2a form a lipid environment essential to maintain BBB integrity (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n1700018O18Rik; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; Major facilitator superfamily domain-containing protein 2A; MFS2A; Mfsd; Mfsd2; Mfsd2a; NLS1; OTTMUSP00000009315; Sodium-dependent LPC symporter 1; Sodium-dependent lysophosphatidylcholine symporter 1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R\nSENSITIVITY: Endogenous\nMW (kDa): 50-60\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800126967977,"sku":"80302T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-80302t","provider":"Iright","version":"1.0","type":"link"}