{"product_id":"cst-80519s","title":"CST,  80519S, CD84 (E4F2N) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CD84 mouse. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CD84 (E4F2N) Rabbit Monoclonal Antibody (CST #80519) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD84 (E4F2N) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD84 protein.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of mouse CD84 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCluster of Differentiation 84 (CD84), also known as signaling lymphocytic activation molecule family member 5 (SLAMF5), is a membrane glycoprotein expressed by numerous immune cell types, including hematopoietic progenitor cells, T cells, B cells, NK cells, macrophages, monocytes, dendritic cells, platelets, mast cells, and thymocytes (1-9). CD84 is a homophilic adhesion molecule involved in modulating the activation, differentiation, proliferation, and cytotoxicity of a wide variety of immune cells, and thus is involved in the regulation and interconnection of both the innate and adaptive immune response (6-14). Certain CD84 activities are regulated by the presence or absence of small cytoplasmic adaptor proteins, SH2D1A\/SAP and\/or SH2D1B\/EAT-2 (5,14). Alternate splicing results in multiple transcript variants.\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nA130013D22Rik; Cd84; CD84 antigen; CDw84; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; SLA; SLAF5; SLAM family member 5; Slamf5\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 45-80\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800126378153,"sku":"80519S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-80519s","provider":"Iright","version":"1.0","type":"link"}