{"product_id":"cst-81055t","title":"CST,  81055T, MPP6\/MPHOSPH6 (F3T9S) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MPHOSPH6. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, MPP6\/MPHOSPH6 (F3T9S) Rabbit Monoclonal Antibody (CST #81055) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMPP6\/MPHOSPH6 (F3T9S) Rabbit Monoclonal Antibody recognizes endogenous levels of total MPP6\/MPHOSPH6 protein. This antibody detects 52 and 54 kDa bands of unknown origin.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala151 of human MPP6\/MPHOSPH6 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nM-phase phosphoprotein 6 (MPP6 or MPHOSPH6) is a nuclear exosome protein that binds to pre-rRNAs to help facilitate the formation of mature 5.8S rRNA (1-3). MPP6, along with other exosome cofactors, can recruit the RNA helicase MTR4 to facilitate decay by unwinding RNA in order for it to enter the exosome core (4-6). MPP6 and YTHDC1 have been shown to play a role in IgH DNA recombination through an m6A-dependent mechanism (7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nM-phase phosphoprotein 6; MPH6; MPHOSPH6; MPP; MPP-6; MPP6\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 20\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799920922793,"sku":"81055T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-81055t","provider":"Iright","version":"1.0","type":"link"}