{"product_id":"cst-83676s","title":"CST,  83676S, CD68 (E3O7V) Feline Chimeric Monoclonal Antibody","description":"Monoclonal Antibody for studying CD68 mouse. Validated for Immunofluorescence (Frozen). Available in 2 sizes. Highly specific and rigorously validated in-house, CD68 (E3O7V) Feline Chimeric Monoclonal Antibody (CST #83676) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nImmunofluorescence (Frozen): 1:50 - 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Immunofluorescence (Frozen)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD68 (E3O7V) Feline Chimeric Monoclonal Antibody recognizes endogenous levels of total CD68 protein.\nSpecies Reactivity: Mouse, Rat, Hamster\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nThis recombinant chimeric antibody is engineered from CD68 (E3O7V) Rabbit mAb #97778 according to animal-free protocols. The chimeric antibody retains its antigen-binding Fab regions from the original rabbit monoclonal antibody, but contains a feline-derived Fc domain. When multiplexing, Fc-directed rabbit secondaries are required to detect rabbit-host primary antibodies. The parent antibody, CD68 (E3O7V) Rabbit mAb #97778, is produced by immunizing animals with mouse CD68 recombinant protein and reacts with an epitope surrounding Gly113.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCd68; CD68 antigen; gp11; gp110; Lamp4; Macrosialin; Sca; Scard1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M R Hm\nSENSITIVITY: Endogenous\nSource\/Isotype: Feline chimeric IgG1","brand":"CST","offers":[{"title":"Default Title","offer_id":46800300474537,"sku":"83676S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-83676s","provider":"Iright","version":"1.0","type":"link"}