{"product_id":"cst-8482s","title":"CST,  8482S, IMP1 (D33A2) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IMP-1. Validated for Western Blotting,Immunoprecipitation,eCLIP. Available in 2 sizes. Highly specific and rigorously validated in-house, IMP1 (D33A2) Rabbit Monoclonal Antibody (CST #8482) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nFor more information about the RBP-eCLIP service please visit Eclipsebio .\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\neCLIP: 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIMP1 (D33A2) Rabbit Monoclonal Antibody recognizes endogenous levels of total IMP1 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human IMP1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nInsulin-like growth factor-II mRNA-binding proteins (IMPs) belong to a family of zipcode-binding proteins (1,2). Three members of this family, IMP1, IMP2, and IMP3, have been identified (1,2). They contain two RNA recognition motifs, four K homology domains, and were found to function in mRNA localization, turnover, and translation control (1,2). Research studies have implicated these proteins in a variety of physiological and pathological processes, such as growth and development (3), testicular neoplasia (4), and melanocytic neoplasia (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCoding region determinant-binding protein; CRD-BP; CRDBP; IF2B1; IGF II mRNA binding protein 1; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IGF2BP1; IMP-1; IMP1; insulin like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; Insulin-like growth factor 2 mRNA-binding protein 1; VICKZ family member 1; VICKZ1; ZBP-1; ZBP1; Zip code-binding protein 1; Zipcode-binding protein 1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 64\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799946875049,"sku":"8482S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-8482s","provider":"Iright","version":"1.0","type":"link"}