{"product_id":"cst-85345t","title":"CST,  85345T, IFIT5 (E4O1Q) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IFIT5. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, IFIT5 (E4O1Q) Rabbit Monoclonal Antibody (CST #85345) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIFIT5 (E4O1Q) Rabbit Monoclonal Antibody recognizes endogenous levels of total IFIT5 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala340 of human IFIT5 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nInterferon-induced protein with tetratricopeptide repeats 5 (IFIT5) is a member of the IFIT family of innate immune effector molecules that participate in defense against viral pathogens. Compared to other IFIT family members, the function of IFIT5 is the least understood. Research studies, however, have shown that IFIT5 contributes to the host innate immune antiviral response, in part, by binding to single-stranded viral RNAs (1,2). In addition, IFIT5 has been shown to enhance activation of NF-kB in response to viral infection (3,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ53857; FLJ92678; IFIT-5; IFIT5; interferon induced protein with tetratricopeptide repeats 5; Interferon-induced 58 kDa protein; Interferon-induced protein with tetratricopeptide repeats 5; ISG58; P58; Retinoic acid- and interferon-inducible 58 kDa protein; retinoic acid- and interferon-inducible protein (58kD); RI58\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 58\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799952019625,"sku":"85345T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-85345t","provider":"Iright","version":"1.0","type":"link"}