{"product_id":"cst-85652s","title":"CST,  85652S, Musashi (D46A8) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Musashi-1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Musashi (D46A8) Rabbit Monoclonal Antibody (CST #85652) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMusashi (D46A8) Rabbit Monoclonal Antibody recognizes endogenous levels of total Musashi-1 and Musashi-2 proteins.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala100 of human Musashi-1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMusashi-1 and Musashi-2 are RNA-binding proteins which play a role in asymmetric cell division of ectodermal precursor cells by regulating the translation of target mRNA. Both family members augment Notch signaling and repress the translation of m-Numb, a protein that positively modulates differentiation of neural stem cells into neurons. Thus, Musashi contributes to the maintenance of neural stem cells (1). While Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells (2-4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nMSI1; MSI1H; musashi 1; musashi homolog 1 (Drosophila); musashi RNA binding protein 1; Musashi-1; musashi1; RNA-binding protein Musashi homolog 1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 35\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799954149545,"sku":"85652S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-85652s","provider":"Iright","version":"1.0","type":"link"}