{"product_id":"cst-86302t","title":"CST,  86302T, FAM96B (D4V9Z) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying FAM96B. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, FAM96B (D4V9Z) Rabbit Monoclonal Antibody (CST #86302) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nFAM96B (D4V9Z) Rabbit Monoclonal Antibody recognizes endogenous levels of total FAM96B protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln21 of human FAM96B protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nIron-sulfur (Fe-S) clusters (ISC) are cofactors for many proteins that display a wide range of biological functions, such as DNA maintenance, transcription, translation, cellular metabolism, electron transport, and oxidative phosphorylation (1). While structurally simple, the synthesis and insertion of ISC into Fe-S proteins are complex processes that involve many different proteins (2). FAM96B, also known as MIP18 (MSS19-interacting protein of 18kDa), is a component of the cytosolic Fe-S protein assembly complex (3,4). FAM96B is in a complex with MMS19 that is responsible for assembly of multiple nuclear Fe-S proteins involved in DNA metabolism (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCGI-128; CGI-128 protein; CIA2B; CIAB; CIAO2B; Cytosolic iron-sulfur assembly component 2B; FAM96B; family with sequence similarity 96 member B; family with sequence similarity 96, member B; MIP18; Mitotic spindle-associated MMXD complex subunit MIP18; MSS19-interacting protein of 18 kDa; Protein FAM96B\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 18\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799959818409,"sku":"86302T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-86302t","provider":"Iright","version":"1.0","type":"link"}